CISC 889 Bioinformatics

Spring semester 2004

Tentative schedule

Date

Topic

Readings

Handouts

Notes

2/10

Overview of the course

 

syllabus

 

2/12

Biology

Kimball's page

 

Dr. Adam Marsh

2/17

Genome sequencing

A primer

 

 

2/19

Sequence pairwise alignment: concepts and algorithms

Chapter 2

 

 

2/24

Sequence pairwise alignment: statistics

Chapter 2

 

 

2/26

Sequence pairwise alignment: heuristics

 

 

HW1 out

3/2

Multiple sequence alignment

Chapter 6

 

 

3/4

Hidden Markov models

Chapter 3

 

 

3/9

Hidden Markov models

Chapter 4

 

 

3/11

Hidden Markov models

Chapter 5

 

HW2 out (HW1 due)

3/16

Gene finding, and motif and domain identification

 

 

 

3/18

Protein Secondary structure prediction

 

 

 

3/23

Spring break

 

 

 

3/25

Spring break

 

 

 

3/30

Phylogenetic analysis

Chapter 7

 

 

4/1

Phylogenetic analysis

Chapter 8

 

 

4/6

Phylogenetic analysis

 

 

HW3 out (HW2 is due)

4/8

Stochastic grammars

Chapter 9

 

 

4/13

RNA alignment and
secondary structure prediction

Chapter 10

 

 

4/15

DNA microarray

 

 

HW4 out (HW3 is due)

4/20

Gene expression profiling (Support vector machines)

 

 

 

4/22

Genetic networks (modeling by Boolean networks)

 

 

 

4/27

Genetic networks (modeling by Bayesian networks)

 

 

 

4/29

Metabolic pathways reconstruction

 

 

HW4 is due

5/4

Proteomics

 

 

 

5/6

TBA

 

 

 

5/11

TBA

 

 

 

5/13

Presentations

 

 

 

5/18

Presentations